Testosterone Propionate: Side Effects, Dosage, Uses and More

Testosterone Propionate is an injectable compound with a slower rate of unesterified testosterone release, but faster than the rest of the esterified testosterone release. Short-Acting ester has some advantages and disadvantages. The main drawback is that users need to inject testosterone propionate at least every two days during the cycle to get the right results. The advantages, however, are easier control and avoidance of possible side effects. As there are fewer esters per bottle, there is also more true testosterone by injection, which leads to better results. The propionate ester prolongs the half-life of testosterone to about 4.5 days.

Side effects of testosterone propionate (and how to neutralize it)

Estrogenic side effects of testosterone:

The main side effects of testosterone propionate are its ability to aromatize estrogen. Testosterone has reasonable estrogenic action: it has a modest similarity for binding to the enzyme aromatase. For this reason, a moderate degree of aromatization is predictable from the use of testosterone. For addressing this problem, there are two solutions:

Selective estrogen receptor modulators (SERMs) including tamoxifen citrate (Nolvadex) or clomiphene (brands: Androxal, Clomid, and Omifin) work by binding to, filling, and preventing genuine estrogen receptors.

Aromatase inhibitors (AI) such as anastrozole (Arimidex) works by inhibiting the aromatase process and even lower levels of estrogen in the body. Flavoring inhibitors are much more effective than SERMs.

Androgenic side effects of testosterone:

Androgenic side effects of testosterone have to do with the fact that testosterone becomes stronger and more potent through the androgen dihydrotestosterone (DHT) enzyme 5-alpha-reductase (5AR).

The 5-alpha-reductase enzyme is abundant in some tissues such as the scalp, prostate, and skin. When testosterone reaches these tissues, it shows a sharp decrease in the stronger androgenic metabolite DHT. DHT is responsible for the greater severity of androgenic side effects.

Hair loss:

This side effect depends entirely on the genetic predisposition of the individual. If there are no bald men in your family, this is not a problem for you. When male baldness occurs in your genes, you still lose your hair, but supplementing with testosterone can speed up the process. It can get counteracted to a degree with Finasteride and Nizoral (ketoconazole) 2% shampoo.


The skin, in turn, increases the chance to clog the pores and form acne. To some extent, it can get neutralized with a 2% Nizoral shampoo containing the active ingredient ketoconazole as a topical DHT blocker in scalp and skin. It will effectively increase the likelihood of androgens causing male pattern baldness, as well as acne-induced acne, an increase in oily skin. Acne is usually removed by suspending steroids not long after completion of the testosterone cycle.


Studies have shown clear associations between testosterone and aggression. Mobile anger is a kind of impulse control: a tendency to overreact to an event that would not normally trigger it.

Testicular narrowing:

When external testosterone is integrated, our natural testosterone production gets reduced. The testes stop producing testosterone because many are from the outside. As a result, they temporarily pull together. We cannot do much against the testicular atrophy during the testosterone cycle. Once the use of external testosterone completes, the natural production of testosterone gradually restores, and the testicles return to their maximum size. Steroid users accelerate recovery by taking clomiphene citrate (brands: Androxal, Clomid and Omifin). HCG (human chorionic gonadotropin) is also used to restore the natural production of testosterone quickly.

Decreased libido:

While they supplement with testosterone, men often notice a greater libido (sexual desire). In the same way, they notice a decrease in libido during the period in which integration with testosterone ends and before the natural production of testosterone is resumed (with clomiphene citrate or HCG).

How is testosterone propionate used?

The most common dose of testosterone propionate is:

  • 50 to 100 mg per day
  • 50 to 100 mg every two days

Every third day must be the absolute minimum because it is close to the time limit of the proposed activity.

The actual use of testosterone propionate

Testosterone Propionate is one of the most popular anabolic steroids 80 years after its invention. It is often used by bodybuilders and athletes to improve physical performance. Testosterone itself is considered the most natural and safe anabolic steroid a person can use. The ester propionate is advisable for the first time for all steroid users.

Effects of Testosterone Propionate (desirable)

There are two desirable main effects of testosterone:

  • Improvement of physical/athletic performance (resistance, strength, faster regeneration)
  • Improvement of the body (muscle building, fat loss)

The remainder of the desirable testosterone effects a person may experience during the steroid cycle include:

  • Increased collagen synthesis and bone mineral content. Collagen is the protein-based building material for connective tissue throughout the body (ligaments, tendons, cartilage, joints, and bones)
  • Higher self-esteem
  • Deeper voice (male)
  • Darkening and thickening of body hair
  • Elevated levels of IGF-1 and MGF hormones (which also promote muscle growth)
  • Increased hemoglobin (erythrocyte count)
  • Anti-catabolic effect on muscle tissue by acting as anti-glucocorticoid

Johnnie Walker

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